Methamphetamine Hcl
A to Z Drug Facts
Methamphetamine Hcl |
(Desoxyephedrine HCl) |
(meth-am-FET-uh-meen HIGH-droe-KLOR-ide) |
Desoxyn |
Tablets |
5 mg |
Class: CNS stimulant, Amphetamine |
Action Activates noradrenergic neurons causing CNS and respiratory stimulation; stimulates the satiety center in the brain, causing appetite suppression.
Indications Treatment of attention deficit disorder in children; short-term exogenous obesity adjunct.
Contraindications Advanced arteriosclerosis; symptomatic cardiovascular disease; moderate to severe hypertension; hyperthyroidism; hypersensitivity to sympathomimetic amines; glaucoma; agitated states; history of drug abuse. Drug should not be used concomitantly with or within 14 days of MAO inhibitor use.
Attention Deficit Disorder
Children: PO 5 mg 1 to 2 times/day; may be increased weekly by 5 mg to max of 20 to 25 mg/day in divided doses.
Exogenous Obesity
Adults and Children Greater Than 12 yr: PO 5 mg 1 to 3 times/day 30 min before meals. Not to be used beyond a few weeks.
Guanethidine
Amphetamines may decrease effectiveness.
MAO Inhibitors, Furazolidone
Hypertensive crisis and intracranial hemorrhage may occur.
Tricyclic Antidepressants
Decreased amphetamine effect.
Urinary Acidifiers
Decreased amphetamine levels.
Urinary Alkalinizers
Increased amphetamine levels.
Lab Test Interferences Plasma and urinary steroid levels may be altered.
CARDIOVASCULAR: Palpitations; tachycardia; hypertension; arrhythmias. CNS: Hyperactivity; dizziness; insomnia; euphoria; restlessness; tremors; headache. DERMATOLOGIC: Urticaria. GI: Dry mouth; unpleasant taste; diarrhea; constipation; anorexia. GU: Impotence.
Pregnancy: Category C. Lactation: Excreted in breast milk. Children: Not recommended as anorectic agent in children less than 12 yr. Drug dependence: Has high potential for dependency and abuse. Tolerance may occur; do not exceed recommended dose. Tartrazine Sensitivity: Some products contain tartrazine, which may cause allergic reactions in susceptible individuals.
PATIENT CARE CONSIDERATIONS |
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Copyright © 2003 Facts and Comparisons
David S. Tatro
A to Z Drug Facts